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HIST2H2AC Antibody - middle region : Biotin (ARP51480_T100-Biotin)

Selected Variant

ARP51480_T100-Biotin

Size: 100 µL

Product Specifications

Gene Name

Histone cluster 2, H2ac

Gene Aliases

H2A, H2A/q, H2AFQ, H2A-GL101, HIST2H2AC

Gene ID

8338

Swiss Prot

Q16777

Accession Number

NP_003508

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human HIST2H2AC

Target

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. HIST2H2AC is a member of the histone H2A family.Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Partner Proteins

BAP1; UBC; RNF2; INO80; UIMC1; RAD6; HDAC2; USP16; AURKB; NEDD8; CUL4A; USP15; SART3; HIST2H2BE; POLR2C; RNF168; HCVgp1; PRAME; RNF8; CRP; CENPA; HIST1H3B; EP300; KAT2A; BRCA1; BARD1; RBBP7; RBBP4; HAT1; ATXN7L3; USP22; MECP2; CHFR; DDB2; HIST1H4A; HIST1H

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 86%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 92%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

14kDa

References & Citations

Zhao, Y., (2008) Mol. Cell 29 (1), 92-101

Shipping Conditions

Wet Ice

Protein Length

129

NCBI Gene Symbol

HIST2H2AC

NCBI GB Accession Number

HIST2H2AC

Host or Source

Rabbit

Protein Name

Histone H2A type 2-C

Nucleotide Accession Number

NM_003517

Peptide Sequence

IPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHKAKSK

Price

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