HIST2H2AC Antibody - middle region: Biotin (ARP51480_T100-Biotin)
Product Specifications
Gene Name
Histone cluster 2, H2ac
Gene Aliases
H2A, H2A/q, H2AFQ, H2A-GL101, HIST2H2AC
Gene ID
8338
Swiss Prot
Q16777
Accession Number
NP_003508
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human HIST2H2AC
Target
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. HIST2H2AC is a member of the histone H2A family.Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Partner Proteins
BAP1; UBC; RNF2; INO80; UIMC1; RAD6; HDAC2; USP16; AURKB; NEDD8; CUL4A; USP15; SART3; HIST2H2BE; POLR2C; RNF168; HCVgp1; PRAME; RNF8; CRP; CENPA; HIST1H3B; EP300; KAT2A; BRCA1; BARD1; RBBP7; RBBP4; HAT1; ATXN7L3; USP22; MECP2; CHFR; DDB2; HIST1H4A; HIST1H
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 86%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 92%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
14kDa
Shipping Conditions
Wet Ice
Protein Length
129
NCBI Gene Symbol
HIST2H2AC
Protein Name
Histone H2A type 2-C
Nucleotide Accession Number
NM_003517
Curated Selection
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