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ASPH Antibody - N-terminal region : Biotin (ARP51357_T100-Biotin)

Product Specifications

Gene Name

Aspartate beta-hydroxylase

Gene Aliases

AAH, BAH, HAAH, JCTN, FDLAB, junctin, CASQ2BP1

Gene ID

444

Swiss Prot

Q9NRI0

Accession Number

NP_064549

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ASPH

Target

ASPH is thought to play an important role in calcium homeostasis. Alternative splicing of this gene results in five transcript variants which vary in protein translation, the coding of catalytic domains, and tissue expression. Variation among these transcripts impacts their functions which involve roles in the calcium storage and release process in the endoplasmic and sarcoplasmic reticulum as well as hydroxylation of aspartic acid and asparagine in epidermal growth factor-like domains of various proteins.This gene is thought to play an important role in calcium homeostasis. Alternative splicing of this gene results in five transcript variants which vary in protein translation, the coding of catalytic domains, and tissue expression. Variation among these transcripts impacts their functions which involve roles in the calcium storage and release process in the endoplasmic and sarcoplasmic reticulum as well as hydroxylation of aspartic acid and asparagine in epidermal growth factor-like domains of various proteins.

Partner Proteins

ASNA1; TARDBP; IQCB1; UBC; NOS2; Htt; APP; CUL3; SQSTM1; TRDN

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

There is BioGPS gene expression data showing that ASPH is expressed in HepG2

Concentration

0.5 mg/ml

Homology

Dog: 93%; Horse: 83%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 86%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

25kDa

References & Citations

Xian, Z.H., (2006) Mod. Pathol. 19 (2), 280-286

Shipping Conditions

Wet Ice

Protein Length

225

NCBI Gene Symbol

ASPH

NCBI GB Accession Number

ASPH

Host or Source

Rabbit

Protein Name

Aspartyl/asparaginyl beta-hydroxylase

Nucleotide Accession Number

NM_020164

Peptide Sequence

SEVLQGKLGIYDADGDGDFDVDDAKVLLEGPSGVAKRKTKAKVKELTKEE

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