PPP3CA Antibody - N-terminal region : Biotin (ARP51337_P050-Biotin)

Product Specifications

Gene Name

Protein phosphatase 3, catalytic subunit, alpha isozyme

Gene Aliases

CALN, CCN1, CNA1, CALNA, DEE91, IECEE, PPP2B, ACCIID, CALNA1, IECEE1

Gene ID

5530

Swiss Prot

P63329

Accession Number

NP_000935

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PPP3CA

Target

PPP3CA belongs to the PPP phosphatase family, PP-2B subfamily. It is a calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. PPP3CA dephosphorylates HSPB1 and SSH1.

Partner Proteins

C16orf74; PPP3R1; JUN; CEP76; MARCH7; VCP; TP53; UBC; SETSIP; P3H1; XPO5; MAT2B; TNPO3; PDIA6; VBP1; TSN; PPP2R2A; PFDN5; NRD1; NASP; TNPO1; HNRNPH1; ALY1; MAPK7; RCAN1; MRI1; RHOC; TRAF3; KCNIP3; PDE4D; PSMA6; PHLPP2; PTEN; AKT1; IRF2; GRB2; Fbxo32; MYOZ

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

59kDa

References & Citations

Shen, X., (2008) J. Biol. Chem. 283 (17), 11407-11413

Shipping Conditions

Wet Ice

Protein Length

521

NCBI Gene Symbol

PPP3CA

NCBI GB Accession Number

PPP3CA

Host or Source

Rabbit

Protein Name

Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform

Nucleotide Accession Number

NM_000944

Peptide Sequence

MSEPKAIDPKLSTTDRVVKAVPFPPSHRLTAKEVFDNDGKPRVDILKAHL

Subunit

Alpha isoform

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