NTRK2 Antibody - C-terminal region : FITC (ARP51316_P050-FITC)
Selected Variant
ARP51316_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
Neurotrophic tyrosine kinase, receptor, type 2
Gene Aliases
OBHD, TRKB, DEE58, trk-B, EIEE58, GP145-TrkB
Gene ID
4915
Swiss Prot
Q8WXJ5
Accession Number
NP_001018075
Host
Rabbit
Reactivity
Human, Rat, Cow, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human NTRK2
Target
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders.
Partner Proteins
TNK2; RANBP9; POLR2G; HSP90AA1; AP1B1; NMNAT1; UBC; NTF4; Nedd4; SHC2; KIDINS220; DOK5; SH2B2; SH2B1; SHC3; RASGRF1; UBB; FRS3; GIPC1; NCK2; DYNLL1; SQSTM1; SHC1; NCK1; NTRK2; PTPN1; PTPN11; PLCG1; NTF3; NGFR; FYN; BDNF; TRAF6; PIK3R1; FRS2
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
IF, WB, IHC
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 88%; Horse: 100%; Human: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
57kDa
Shipping Conditions
Wet Ice
Protein Length
553
NCBI Gene Symbol
NTRK2
NCBI GB Accession Number
NTRK2
Host or Source
Rabbit
Protein Name
BDNF/NT-3 growth factors receptor
Nucleotide Accession Number
NM_001018065
Peptide Sequence
DFSWFGFGKVKSRQGVGPASVISNDDDSASPLHHISNGSNTPSSSEGGPD
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