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PEG10 Antibody - N-terminal region : FITC (ARP51313_P050-FITC)

Selected Variant

ARP51313_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Paternally expressed 10

Gene Aliases

EDR, HB-1, Mar2, RTL2, MEF3L, Mart2, RGAG3, SIRH1

Gene ID

23089

Swiss Prot

Q86TG7

Accession Number

NP_055883

Host

Rabbit

Reactivity

Human, Mouse, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human PEG10

Target

This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene.

Partner Proteins

SIAH1; FAM127C; LDOC1; CALCOCO2; FAM127A; UBC; MAPT; HNRNPUL1; HNRNPH1; BAG1; TGFBR2; TGFBR1; BMPR1B; BMPR1A; ACVRL1; ACVR2B; ACVR2A; ACVR1B; ACVR1; RNF2; ZNF512B; RNF181; HMGCS1; TOLLIP; IRF4; SIAH2

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

80kDa

Shipping Conditions

Wet Ice

Protein Length

708

NCBI Gene Symbol

PEG10

NCBI GB Accession Number

PEG10

Host or Source

Rabbit

Protein Name

Retrotransposon-derived protein PEG10

Nucleotide Accession Number

NM_015068

Peptide Sequence

SMMTGRAARWASAKLERSHYLMHNYPAFMMEMKHVFEDPQRREVAKRKIR

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