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PHC2 Antibody - C-terminal region: Biotin (ARP51253_P050-Biotin)

Product Specifications

Gene Name

Polyhomeotic homolog 2 (Drosophila)

Gene Aliases

PH2, EDR2, HPH2

Gene ID

1912

Swiss Prot

Q8IXK0

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human PHC2

Target

In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

FAM74A4; FAM74A1; FAM13C; FAM124A; MAGEB6; ZMAT2; ZNF417; MAB21L3; SSX2IP; TRIM41; ZGPAT; L3MBTL3; PCGF5; SPATC1L; FAM161A; ENKD1; KBTBD7; SYT16; THAP7; AEN; CARD9; CBX8; C1orf109; SFMBT1; PRPF31; PPP1R16B; KAT5; PCGF3; RWDD2B; ZBTB24; MORF4L2; RBM39; AP1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity purified

Concentration

0.5 mg/mL

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

94kDa

Shipping Conditions

Wet Ice

Protein Length

858

NCBI Gene Symbol

PHC2

Protein Name

Polyhomeotic-like protein 2

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