PHC2 Antibody - N-terminal region : FITC (ARP51251_P050-FITC)
Selected Variant
ARP51251_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
Polyhomeotic homolog 2 (Drosophila)
Gene Aliases
PH2, EDR2, HPH2
Gene ID
1912
Swiss Prot
Q8IXK0
Accession Number
NP_932157
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human PHC2
Target
In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.
Partner Proteins
FAM74A4; FAM74A1; FAM13C; FAM124A; MAGEB6; ZMAT2; ZNF417; MAB21L3; SSX2IP; TRIM41; ZGPAT; L3MBTL3; PCGF5; SPATC1L; FAM161A; ENKD1; KBTBD7; SYT16; THAP7; AEN; CARD9; CBX8; C1orf109; SFMBT1; PRPF31; PPP1R16B; KAT5; PCGF3; RWDD2B; ZBTB24; MORF4L2; RBM39; AP1
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
91kDa
Shipping Conditions
Wet Ice
Protein Length
858
NCBI Gene Symbol
PHC2
NCBI GB Accession Number
PHC2
Host or Source
Rabbit
Protein Name
Polyhomeotic-like protein 2
Nucleotide Accession Number
NM_198040
Peptide Sequence
GGSGRPTGPQISVYSGIPDRQTVQVIQQALHRQPSTAAQYLQQMYAAQQQ
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