NEDD9 Antibody - middle region : HRP (ARP51211_P050-HRP)
Product Specifications
Gene Name
Neural precursor cell expressed, developmentally down-regulated 9
Gene Aliases
CAS2, CASL, HEF1, CAS-L, CASS2
Gene ID
4739
Swiss Prot
Q14511
Accession Number
NP_006394
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human NEDD9
Target
Variation in NEDD9 is associated wih susceptibility to late-onset Alzheimer and Parkinson diseases. Changes in expression of the scaffold protein HEF1/CAS-L/NEDD9 were found to be a potent prometastatic stimulus in melanoma and other cancers.
Partner Proteins
NFKBIA; NAB2; RFX6; PRR20A; BANP; RBPMS; BCAR3; TRIP6; TRIM27; REL; SMAD1; APP; CRK; UBC; PIK3CA; DIMT1; ELSPBP1; NEDD9; ITCH; CHAT; MICAL1; SH2D3C; SMAD3; BCAR1; PXN; CRKL; ZYX; SMAD2; PTK2B; PTK2; NCK1; ID2; RAPGEF1; PTPN12; CDH1; ABL1; PTPN11; LYN; LCK
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB, IHC
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 86%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
93kDa
References & Citations
Li, Y., (2008) Hum. Mol. Genet. 17 (5), 759-767
Shipping Conditions
Wet Ice
Protein Length
834
NCBI Gene Symbol
NEDD9
NCBI GB Accession Number
NEDD9
Host or Source
Rabbit
Protein Name
Enhancer of filamentation 1
Nucleotide Accession Number
NM_006403
Peptide Sequence
DLVDGINRLSFSSTGSTRSNMSTSSTSSKESSLSASPAQDKRLFLDPDTA
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