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NEDD9 Antibody - middle region: FITC (ARP51211_P050-FITC)

Product Specifications

Gene Name

Neural precursor cell expressed, developmentally down-regulated 9

Gene Aliases

CAS2, CASL, HEF1, CAS-L, CASS2

Gene ID

4739

Swiss Prot

Q14511

Accession Number

NP_006394

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human NEDD9

Target

Variation in NEDD9 is associated wih susceptibility to late-onset Alzheimer and Parkinson diseases. Changes in expression of the scaffold protein HEF1/CAS-L/NEDD9 were found to be a potent prometastatic stimulus in melanoma and other cancers.

Partner Proteins

NFKBIA; NAB2; RFX6; PRR20A; BANP; RBPMS; BCAR3; TRIP6; TRIM27; REL; SMAD1; APP; CRK; UBC; PIK3CA; DIMT1; ELSPBP1; NEDD9; ITCH; CHAT; MICAL1; SH2D3C; SMAD3; BCAR1; PXN; CRKL; ZYX; SMAD2; PTK2B; PTK2; NCK1; ID2; RAPGEF1; PTPN12; CDH1; ABL1; PTPN11; LYN; LCK

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Cow: 86%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

93kDa

Shipping Conditions

Wet Ice

Protein Length

834

NCBI Gene Symbol

NEDD9

Protein Name

Enhancer of filamentation 1

Nucleotide Accession Number

NM_006403

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