NEDD9 Antibody - middle region : Biotin (ARP51210_T100-Biotin)

Product Specifications

Gene Name

Neural precursor cell expressed, developmentally down-regulated 9

Gene Aliases

CAS2, CASL, HEF1, CAS-L, CASS2

Gene ID

4739

Swiss Prot

Q14511

Accession Number

NP_006394

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human NEDD9

Target

Variation in NEDD9 is associated wih susceptibility to late-onset Alzheimer and Parkinson diseases. Changes in expression of the scaffold protein HEF1/CAS-L/NEDD9 were found to be a potent prometastatic stimulus in melanoma and other cancers.

Partner Proteins

NFKBIA; NAB2; RFX6; PRR20A; BANP; RBPMS; BCAR3; TRIP6; TRIM27; REL; SMAD1; APP; CRK; UBC; PIK3CA; DIMT1; ELSPBP1; NEDD9; ITCH; CHAT; MICAL1; SH2D3C; SMAD3; BCAR1; PXN; CRKL; ZYX; SMAD2; PTK2B; PTK2; NCK1; ID2; RAPGEF1; PTPN12; CDH1; ABL1; PTPN11; LYN; LCK

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

NEDD9 is strongly supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 93%; Guinea Pig: 79%; Horse: 93%; Human: 100%; Mouse: 92%; Rabbit: 79%; Rat: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.