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TEC Antibody - middle region: FITC (ARP51209_P050-FITC)

Product Specifications

Gene Name

Tec protein tyrosine kinase

Gene Aliases

PSCTK4

Gene ID

7006

Swiss Prot

P42680

Accession Number

NP_003206

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human TEC

Target

The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.

Partner Proteins

ERBB2; MED28; GRB2; SHC1; FASLG; Nedd4; UBC; IKBKG; STAP1; PIP4K2A; PLK4; PTPN18; PIK3R3; GNA12; SOCS1; PIP5K1A; PTPN21; DOK1; TEC; PLCG2; WAS; BTK; BMX; TP53; PRLR; PLCG1; PIK3R1; LYN; KIT; VAV1; JAK2; JAK1; ARHGEF12; GNA13; RHOA; RAC1; PIK3R2

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

73kDa

Shipping Conditions

Wet Ice

Protein Length

631

NCBI Gene Symbol

TEC

Protein Name

Tyrosine-protein kinase Tec

Nucleotide Accession Number

NM_003215

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