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CDR2 Antibody - N-terminal region : HRP (ARP51161_T100-HRP)

Product Specifications

Gene Name

Cerebellar degeneration-related protein 2, 62kDa

Gene Aliases

Yo, CDR62

Gene ID

1039

Swiss Prot

Q01850

Accession Number

NP_001793

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CDR2

Target

Cdr2 normally sequesters c-Myc in the neuronal cytoplasm, thereby down-regulating c-Myc activity, and suggest a mechanism whereby inhibition of cdr2 function by autoantibodies in PCD may contribute to Purkinje neuronal.

Partner Proteins

SMARCE1; CEP57L1; KANSL1; CCDC153; C4orf46; TXLNA; ALS2CR11; C1orf216; HAUS1; ANKRD36BP1; TCHP; FAM161A; ENKD1; FAM110A; LENG1; SCNM1; SH2D4A; LIN37; RCOR3; TBC1D22B; WDYHV1; CCHCR1; AMOTL2; FZR1; RSPH14; CHIC2; MRPL28; TMCC2; HDAC4; EIF4E2; TTR; COX5B; T

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

IHC, WB

Sample Type

CDR2 is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

52kDa

References & Citations

Balbo, M., (2005) FEMS Microbiol. Lett. 249 (2), 359-366

Shipping Conditions

Wet Ice

Protein Length

454

NCBI Gene Symbol

CDR2

NCBI GB Accession Number

CDR2

Host or Source

Rabbit

Protein Name

Cerebellar degeneration-related protein 2

Nucleotide Accession Number

NM_001802

Peptide Sequence

MLAENLVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQ

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