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APOH Antibody - N-terminal region : Biotin (ARP51158_P050-Biotin)

Product Specifications

Gene Name

Apolipoprotein H (beta-2-glycoprotein I)

Gene Aliases

BG, B2G1, B2GP1

Gene ID

350

Swiss Prot

P02749

Accession Number

NP_000033

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human APOH

Target

Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections.Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections.

Partner Proteins

UBC; ATP4A; CLEC4G; TP53; RBBP6; GRB2; GEM; CDC42; AKT1; LRP8; LRP2; F12; F10; PLG; LPA; ANXA2

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Sample Type

APOH is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 85%; Pig: 100%; Rabbit: 92%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

36kDa

References & Citations

Fischetti, F., (2005) Blood 106 (7), 2340-2346

Shipping Conditions

Wet Ice

Protein Length

345

NCBI Gene Symbol

APOH

NCBI GB Accession Number

APOH

Host or Source

Rabbit

Protein Name

Beta-2-glycoprotein 1

Nucleotide Accession Number

NM_000042

Peptide Sequence

LWPINTLKCTPRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGAD

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