YBX1 Antibody - C-terminal region : Biotin (ARP50946_P050-Biotin)

YBX1 binds to splice sites in pre-mRNA and regulates splice site selection. YBX1 binds and stabilizes cytoplasmic mRNA. YBX1 contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. YBX1 binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. YBX1 regulates the transcription of numerous genes. YBX1 promotes separation of DNA strands that contain mismatches or are modified by cisplatin. YBX1 has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro) . YBX1 may play a role in DNA repair. YBX1 is the component of the CRD-mediated complex that promotes MYC mRNA stability.

UBC; TP53; AKT1; SPRTN; AURKA; SUMO2; STAU1; IVNS1ABP; SMURF2; EZH2; BMI1; SUZ12; RNF2; HNRNPU; HNRNPAB; HNRNPA2B1; FUS; FKBP3; DYNC1LI2; DYNC1I2; DYNC1H1; DDX1; APBB1; G3BP1; EIF2B2; TUBB; PRPF40A; EIF3K; DIMT1; TUBA4A; RPL23A; PTBP1; PA2G4; NMT1; MAP2

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.