RBBP8 Antibody - middle region: FITC (ARP50888_P050-FITC)
Product Specifications
Gene Name
Retinoblastoma binding protein 8
Gene Aliases
RIM, COM1, CTIP, JWDS, SAE2, SCKL2
Gene ID
5932
Swiss Prot
A6NKN2
Accession Number
NP_976037
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human RBBP8
Target
RBBP8 is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.
Partner Proteins
LMO4; PIN1; LMO1; MDM2; BRCA1; RBL1; TMEM54; PRRG4; RGS17; IKBKG; IGFBP7; EEF1A1; CTBP2; CLU; MAP2K4; RAF1; RBL2; PCNA; ZNF350; NBN; UIMC1; PALB2; BARD1; SPEN; RAD50; CTBP1; RB1; UBC; FXR2; RBBP8; IKZF1; LIMS1; SIAH2; SIAH1; LMO2; WDYHV1; ATM; TGIF2; IKZF
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
RBBP8 is supported by BioGPS gene expression data to be expressed in ACHN
Concentration
0.5 mg/mL
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
98kDa
Shipping Conditions
Wet Ice
Protein Length
867
NCBI Gene Symbol
RBBP8
Protein Name
DNA endonuclease RBBP8 Ensembl ENSP00000382630
Nucleotide Accession Number
NM_203292
Curated Selection
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