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RBBP8 Antibody - middle region : Biotin (ARP50888_P050-Biotin)

Product Specifications

Gene Name

Retinoblastoma binding protein 8

Gene Aliases

RIM, COM1, CTIP, JWDS, SAE2, SCKL2

Gene ID

5932

Swiss Prot

A6NKN2

Accession Number

NP_976037

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human RBBP8

Target

RBBP8 is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined.

Partner Proteins

LMO4; PIN1; LMO1; MDM2; BRCA1; RBL1; TMEM54; PRRG4; RGS17; IKBKG; IGFBP7; EEF1A1; CTBP2; CLU; MAP2K4; RAF1; RBL2; PCNA; ZNF350; NBN; UIMC1; PALB2; BARD1; SPEN; RAD50; CTBP1; RB1; UBC; FXR2; RBBP8; IKZF1; LIMS1; SIAH2; SIAH1; LMO2; WDYHV1; ATM; TGIF2; IKZF

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

RBBP8 is supported by BioGPS gene expression data to be expressed in ACHN

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

98kDa

Shipping Conditions

Wet Ice

Protein Length

867

NCBI Gene Symbol

RBBP8

NCBI GB Accession Number

RBBP8

Host or Source

Rabbit

Protein Name

DNA endonuclease RBBP8 Ensembl ENSP00000382630

Nucleotide Accession Number

NM_203292

Peptide Sequence

CQQKKEKRNWLPAQDTDSATFHPTHQRIFGKLVFLPLRLVWKEVILRKIL

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