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MDFIC Antibody - N-terminal region : FITC (ARP50877_P050-FITC)

Product Specifications

Gene Name

MyoD family inhibitor domain containing

Gene Aliases

HIC, MDFIC1

Gene ID

29969

Swiss Prot

Q9P1T7

Accession Number

NP_951038

Host

Rabbit

Reactivity

Human, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human MDFIC

Target

MDFIC is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization; p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain.This gene product is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression. Alternative translation initiation from an upstream non-AUG (GUG), and an in-frame, downstream AUG codon, results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localization; p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus. Both isoforms have transcriptional regulatory activity that is attributable to the cysteine-rich C-terminal domain.

Partner Proteins

SOCS4; tat; RPS6KA5; CSNK2A1; MDFIC; CDK9; CCNT1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%; Rabbit: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

37kDa

References & Citations

Gautier, V.W., (2005) Proc. Natl. Acad. Sci. U.S.A. 102 (45), 16362-16367

Shipping Conditions

Wet Ice

Protein Length

355

NCBI Gene Symbol

MDFIC

NCBI GB Accession Number

MDFIC

Host or Source

Rabbit

Protein Name

MyoD family inhibitor domain-containing protein

Nucleotide Accession Number

NM_199072

Peptide Sequence

SVRPAGRRARRQRRGAGSAERPMSGAGEALAPGPVGPQRVAEAGGGQLGS

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