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ZFYVE1 Antibody - C-terminal region : HRP (ARP50843_P050-HRP)

Product Specifications

Gene Name

Zinc finger, FYVE domain containing 1

Gene Aliases

SR3, DFCP1, TAFF1, ZNFN2A1, PPP1R172

Gene ID

53349

Swiss Prot

Q9HBF4

Accession Number

NP_067083

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human ZFYVE1

Target

ZFYVE1 contains two zinc-binding FYVE domains in tandem. This protein binds to phosphatidylinositol-3-phosphate (PtdIns3P) through its FYVE-type zinc finger. It displays a predominantly Golgi, endoplasmic reticulum and vesicular distribution. Alternatively spliced transcript variants have been found for this gene, and they encode two isoforms with different sizes.The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate (PtdIns (3) P) -containing membranes. This gene encodes a protein which contains two zinc-binding FYVE domains in tandem. This protein displays a predominantly Golgi, endoplasmic reticulum and vesicular distribution. Alternatively spliced transcript variants have been found for this gene, and they encode two isoforms with different sizes.

Partner Proteins

UBC; PPP1CA; APP; TRIM13; BCL2L1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 86%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

87kDa

References & Citations

Wan, D., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (44), 15724-15729

Shipping Conditions

Wet Ice

Product Datasheet

Anti-ZFYVE1 (ARP50843_P050-HRP) antibody

Protein Length

777

NCBI Gene Symbol

ZFYVE1

NCBI GB Accession Number

ZFYVE1

Host or Source

Rabbit

Protein Name

Zinc finger FYVE domain-containing protein 1

Nucleotide Accession Number

NM_021260

Peptide Sequence

VCDNCYEARNVQLAVTEAQVDDEGGTLIARKVGEAVQNTLGAVVTAIDIP

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