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CTBP2 Antibody - C-terminal region : Biotin (ARP50670_P050-Biotin)

Product Specifications

Gene Name

C-terminal binding protein 2

Gene ID

1488

Swiss Prot

P56545

Accession Number

NP_073713

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human CTBP2

Target

This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely.This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10.

Partner Proteins

NOL4; TGIF1; HOXB5; NOL4L; FUNDC1; FOXP2; RIMBP3; LCOR; ZNF750; DMRTB1; TSHZ3; BCAS3; BAZ2B; PLCB1; IKZF2; RAI2; ZBTB18; IKZF1; CTBP1; FLI1; SUMO2; SUMO3; SPRTN; SMAD6; UBC; SUMO1; NEDD8; TRNT1; DDX19B; SGTA; DYRK1B; NRIP1; ZNF512B; C15orf39; CTPS2; PPP1R

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Sample Type

CTBP2 is strongly supported by BioGPS gene expression data to be expressed in HeLa

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 86%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

106kDa

References & Citations

Dammer, E.B. (2008) J. Biol. Chem. 283 (11), 6925-6934

Shipping Conditions

Wet Ice

Protein Length

985

NCBI Gene Symbol

CTBP2

NCBI GB Accession Number

CTBP2

Host or Source

Rabbit

Protein Name

C-terminal-binding protein 2

Nucleotide Accession Number

NM_022802

Peptide Sequence

TGRIPESLRNCVNKEFFVTSAPWSVIDQQAIHPELNGATYRYPPGIVGVA

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