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BRF2 Antibody - N-terminal region : Biotin (ARP50630_P050-Biotin)

Product Specifications

Gene Name

BRF2, subunit of RNA polymerase III transcription initiation factor, BRF1-like

Gene Aliases

BRFU, TFIIIB50

Gene ID

55290

Swiss Prot

Q9HAW0

Accession Number

NP_060780

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human BRF2

Target

BRF2 is the general activator of RNA polymerase III transcription. BRF2 is the factor exclusively required for RNA polymerase III transcription of genes with promoter elements upstream of the initiation sites.This gene encodes one of the multiple subunits of the RNA polymerase III transcription factor complex required for transcription of genes with promoter elements upstream of the initiation site. The product of this gene, a TFIIB-like factor, is directly recruited to the TATA-box of polymerase III small nuclear RNA gene promoters through its interaction with the TATA-binding protein.

Partner Proteins

UBC; SNAPC4; TBP; RBL2; IPO4; RNF219; XPO4; SMAP1; SMPD4; FANCI; ATAD3A; TMEM33; DNAAF5; OTUD4; PTPLAD1; GEMIN4; NOC2L; TNPO3; SF3B1; XPO6; XPO7; COPG1; GCN1L1; NUP93; AIFM1; DPM1; SLC3A2; ABCD3; MYO1B; MARS

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

46kDa

References & Citations

Ewing, R.M., Mol. Syst. Biol. 3, 89 (2007)

Shipping Conditions

Wet Ice

Protein Length

419

NCBI Gene Symbol

BRF2

NCBI GB Accession Number

BRF2

Host or Source

Rabbit

Protein Name

Transcription factor IIIB 50 kDa subunit

Nucleotide Accession Number

NM_018310

Peptide Sequence

VTEGVLTTTFSDEGNLREVTYSRSTGENEQVSRSQQRGLRRVRDLCRVLQ

Frequently Asked Questions

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