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ING4 Antibody - middle region : HRP (ARP50608_P050-HRP)

Product Specifications

Gene Name

Inhibitor of growth family, member 4

Gene Aliases

My036, p29ING4

Gene ID

51147

Swiss Prot

Q9UNL4

Accession Number

NP_057246

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ING4

Target

ING4 is a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway.This gene encodes a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed that encode distinct proteins.

Partner Proteins

NAV2; GADD45A; SUV39H1; RELA; CDC34; HIST3H3; MSX1; TP53; PADI4; ING4; KAT7; JADE1; UBC; HIST1H3A; TLX3; JADE2; HOXB9; Trp53; EGLN1; G3BP2; PPFIA1; UBE2D2; EP300; HHT2; HHT1; HIST2H3C; JADE3; MEAF6; CDKN2A

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

ING4 is supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 87%; Guinea Pig: 87%; Horse: 87%; Human: 100%; Mouse: 100%; Rabbit: 87%; Rat: 87%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

28kDa

References & Citations

Li, X., (2008) Anat Rec (Hoboken) 291 (5), 593-600

Shipping Conditions

Wet Ice

Protein Length

248

NCBI Gene Symbol

ING4

NCBI GB Accession Number

ING4

Host or Source

Rabbit

Protein Name

Inhibitor of growth protein 4

Nucleotide Accession Number

NM_016162

Peptide Sequence

DLKEKQIESSDYDSSSSKGKKSRTQKEKKAARARSKGKNSDEEAPKTAQK

Frequently Asked Questions

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