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ING4 Antibody - middle region : Biotin (ARP50608_P050-Biotin)

Product Specifications

Gene Name

Inhibitor of growth family, member 4

Gene Aliases

My036, p29ING4

Gene ID

51147

Swiss Prot

Q9UNL4

Accession Number

NP_057246

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ING4

Target

ING4 is a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway.This gene encodes a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed that encode distinct proteins.

Partner Proteins

NAV2; GADD45A; SUV39H1; RELA; CDC34; HIST3H3; MSX1; TP53; PADI4; ING4; KAT7; JADE1; UBC; HIST1H3A; TLX3; JADE2; HOXB9; Trp53; EGLN1; G3BP2; PPFIA1; UBE2D2; EP300; HHT2; HHT1; HIST2H3C; JADE3; MEAF6; CDKN2A

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

ING4 is supported by BioGPS gene expression data to be expressed in HEK293T

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 87%; Guinea Pig: 87%; Horse: 87%; Human: 100%; Mouse: 100%; Rabbit: 87%; Rat: 87%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

28kDa

References & Citations

Li, X., (2008) Anat Rec (Hoboken) 291 (5), 593-600

Shipping Conditions

Wet Ice

Protein Length

248

NCBI Gene Symbol

ING4

NCBI GB Accession Number

ING4

Host or Source

Rabbit

Protein Name

Inhibitor of growth protein 4

Nucleotide Accession Number

NM_016162

Peptide Sequence

DLKEKQIESSDYDSSSSKGKKSRTQKEKKAARARSKGKNSDEEAPKTAQK

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