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APC2 Antibody - middle region : Biotin (ARP50526_P050-Biotin)

Product Specifications

Gene Name

Adenomatosis polyposis coli 2

Gene Aliases

APCL

Gene ID

10297

Swiss Prot

Q9UJX6

Accession Number

NP_005874

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human APC2

Target

APC2 belongs to the adenomatous polyposis coli (APC) family. It contains 6 ARM repeats. APC2 promotes rapid degradation of CTNNB1 and may function as a tumor suppressor. It may function in Wnt signaling.

Partner Proteins

CTNNB1; NFX1; UBC; CDC27; ANAPC4; ANAPC10; CDC16; CDC23; ANAPC11; ANAPC7; ANAPC5; CDC26; CDH1; ANAPC1; MAPRE3; MAPRE1; Axin1; AXIN2; ACTA1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

244kDa

References & Citations

Attard, T.M., (2008) Dis. Colon Rectum 51 (2), 207-212

Shipping Conditions

Wet Ice

Protein Length

2303

NCBI Gene Symbol

APC2

NCBI GB Accession Number

APC2

Host or Source

Rabbit

Protein Name

Anaphase-promoting complex subunit 2

Nucleotide Accession Number

NM_005883

Peptide Sequence

LAVARIDQLVEDISALHTSSDDSFSLSSGDPGQEAPREGRAQSCSPCRGP

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