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MDFI Antibody - middle region : FITC (ARP50514_P050-FITC)

Selected Variant

ARP50514_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

MyoD family inhibitor

Gene Aliases

I-MF, I-mfa

Gene ID

4188

Swiss Prot

Q99750

Accession Number

NP_005577

Host

Rabbit

Reactivity

Human, Cow, Dog, Pig, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of Human MDFI

Target

This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.

Partner Proteins

PDIA5; USP20; ARID5A; ZNF266; KAT5; SPRY2; SPRY1; NR1H3; ZBTB24; ARHGAP32; KIAA0040; CREB5; MAGED1; ZNF264; GTF3C5; APLN; AKAP17A; ZNF230; ZNF223; ZNF155; ZNF138; ZNF136; ZNF124; ZNF79; WNT11; VHL; NR1H2; TYRO3; TNP2; TNNI1; TGIF1; GNAI2; GATA2; EIF4A2; D

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity purified

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 79%; Human: 100%; Pig: 86%; Rabbit: 79%; Sheep: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

27kDa

Shipping Conditions

Wet Ice

Protein Length

246

NCBI Gene Symbol

MDFI

NCBI GB Accession Number

MDFI

Host or Source

Rabbit

Protein Name

MyoD family inhibitor

Peptide Sequence

AVTCQPQGNPLGCTPLLPNDSGHPSELGGTRRAGNGALGGPKAHRKLQTH

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