MDFI Antibody - middle region : Biotin (ARP50514_P050-Biotin)
Product Specifications
Gene Name
MyoD family inhibitor
Gene Aliases
I-MF, I-mfa
Gene ID
4188
Swiss Prot
Q99750
Accession Number
NP_005577
Host
Rabbit
Reactivity
Human, Cow, Dog, Pig, Rabbit, Sheep
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human MDFI
Target
This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.
Partner Proteins
PDIA5; USP20; ARID5A; ZNF266; KAT5; SPRY2; SPRY1; NR1H3; ZBTB24; ARHGAP32; KIAA0040; CREB5; MAGED1; ZNF264; GTF3C5; APLN; AKAP17A; ZNF230; ZNF223; ZNF155; ZNF138; ZNF136; ZNF124; ZNF79; WNT11; VHL; NR1H2; TYRO3; TNP2; TNNI1; TGIF1; GNAI2; GATA2; EIF4A2; D
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity purified
Concentration
0.5 mg/ml
Homology
Cow: 79%; Dog: 79%; Human: 100%; Pig: 86%; Rabbit: 79%; Sheep: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
27kDa
Shipping Conditions
Wet Ice
Product Datasheet
Anti-MDFI (ARP50514_P050-Biotin) antibody
Protein Length
246
NCBI Gene Symbol
MDFI
NCBI GB Accession Number
MDFI
Host or Source
Rabbit
Protein Name
MyoD family inhibitor
Peptide Sequence
AVTCQPQGNPLGCTPLLPNDSGHPSELGGTRRAGNGALGGPKAHRKLQTH
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