ING1 Antibody - N-terminal region : Biotin (ARP50511_P050-Biotin)
Product Specifications
Gene Name
Inhibitor of growth family, member 1
Gene Aliases
P33, p47, p33ING1, p24ING1c, p33ING1b, p47ING1a
Gene ID
3621
Swiss Prot
Q9UK53
Accession Number
NP_005528
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human ING1
Target
ING1 is a tumor suppressor protein that can induce cell growth arrest and apoptosis. The protein is a nuclear protein that physically interacts with the tumor suppressor protein TP53 and is a component of the p53 signaling pathway. Reduced expression and rearrangement of ING1 gene have been detected in various cancers.
Partner Proteins
SIRT1; SIRT2; UBC; HDAC1; KIAA0101; PCNA; RBP1; RBBP7; RBBP4; HDAC2; BRMS1L; SIN3A; BRMS1; SAP30; ELAVL1; SMURF1; COPS2; NQO1; HIST2H3C; MRGBP; YWHAZ; YWHAH; YWHAG; YWHAE; YWHAB; KPNA2; KPNB1; YWHAQ; SFN; ESR1; LMNA; CDKN2A; TP53; KAT2B; DMAP1; EP300; HHT
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
ING1 is strongly supported by BioGPS gene expression data to be expressed in 721_B, HeLa
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
47kDa
Shipping Conditions
Wet Ice
Protein Length
422
NCBI Gene Symbol
ING1
NCBI GB Accession Number
ING1
Host or Source
Rabbit
Protein Name
Inhibitor of growth protein 1
Nucleotide Accession Number
NM_005537
Peptide Sequence
SPAERLVAEADEGGPSAITGMGLCFRCLLFSFSGRSGVEGGRVDLNVFGS
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