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PHF12 Antibody - C-terminal region : Biotin (ARP50416_P050-Biotin)

Product Specifications

Gene Name

PHD finger protein 12

Gene Aliases

PF1

Gene ID

57649

Swiss Prot

Q96QT6

Accession Number

NP_001028733

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human PHF12

Target

PHF12 acts as a transcriptional repressor. It is involved in recruitment of functional SIN3A complexes to DNA. PHF12 represses transcription at least in part through the activity of an associated histone deacetylase (HDAC) . IT may also repress transcription in a SIN3A-independent manner through recruitment of functional AES complexes to DNA.

Partner Proteins

MORF4L1; HDAC1; UBC; BRCA1; MORF4L2; SIN3A; SAP30

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

110kDa

References & Citations

Nousiainen, M., (2006) Proc. Natl. Acad. Sci. U.S.A. 103 (14), 5391-5396

Shipping Conditions

Wet Ice

Protein Length

1004

NCBI Gene Symbol

PHF12

NCBI GB Accession Number

PHF12

Host or Source

Rabbit

Protein Name

PHD finger protein 12

Nucleotide Accession Number

NM_001033561

Peptide Sequence

NVLYSCDFSEKTPPTPPSSIVAKVQSVIRRRRHQKQDEEPSEEAAMMSSQ

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