LIN28B Antibody - C-terminal region : Biotin (ARP50332_P050-Biotin)
Selected Variant
ARP50332_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Lin-28 homolog B
Gene Aliases
CSDD2
Gene ID
389421
Swiss Prot
Q6ZN17
Accession Number
NP_001004317
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human LN28B
Target
The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation.
Partner Proteins
LARP4; ZCCHC3; NIFK; NHP2; NOP10; PHAX; LARP7; TRUB2; PTCD1; RBM34; NCBP2; RALY; KRR1; EIF4A3; SNRPG; SNRPF; SNRPB2; SNRPA; PURB; PURA; NCBP1; FBL; ELAVL2; TRIM71; UBC; COPS5; USP36
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 93%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 79%; Pig: 100%; Rabbit: 86%; Rat: 93%; Sheep: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
27kDa
Shipping Conditions
Wet Ice
Protein Length
250
NCBI Gene Symbol
LIN28B
NCBI GB Accession Number
LIN28B
Host or Source
Rabbit
Protein Name
Protein lin-28 homolog B
Peptide Sequence
GCTSPPFPQEARAEISERSGRSPQEASSTKSSIAPEEQSKKGPSVQKRKK
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