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ASB5 Antibody - C-terminal region : Biotin (ARP50276_P050-Biotin)

Product Specifications

Gene Name

Ankyrin repeat and SOCS box containing 5

Gene Aliases

ASB-5

Gene ID

140458

Swiss Prot

Q8WWX0

Accession Number

NP_543150

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human ASB5

Target

ASB5 is a member of the¡¡ankyrin repeat and SOCS box-containing (ASB) family of proteins.¡¡They contain ankyrin repeat sequence and SOCS box domain. The SOCS¡¡box serves to couple suppressor of cytokine signalling (SOCS) ¡¡proteins and their binding partners with the elongin B and C¡¡complex, possibly targeting them for degradation.The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known.

Partner Proteins

ENO2; CRYAB; BSG; ATP5C1; ATP5B; ATP2A2; AKR1B1; SLIRP; HIF1AN; ASB1; GCN1L1; LRPPRC; CUL5; TCEB2; TCEB1; SLC3A2; RPN1; RAB1A; PTS; PRKDC; PPP2CB; DNAJA1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 86%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

36kDa

References & Citations

Kile, B.T., (2002) Trends Biochem. Sci. 27 (5), 235-241

Shipping Conditions

Wet Ice

Protein Length

329

NCBI Gene Symbol

ASB5

NCBI GB Accession Number

ASB5

Host or Source

Rabbit

Protein Name

Ankyrin repeat and SOCS box protein 5

Nucleotide Accession Number

NM_080874

Peptide Sequence

LLLEFGADINAKNTELLRPIDVATSSSMVERILLQHEATPSSLYQLCRLC

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