COX3 Antibody - C-terminal region : Biotin (ARP50251_P050-Biotin)
Selected Variant
ARP50251_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Cytochrome c oxidase III
Gene Aliases
COIII, MTCO3
Gene ID
4514
Accession Number
NP_536849
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human COX3
Target
COX3 is a multi-pass membrane protein. It belongs to the cytochrome c oxidase subunit 3 family. Defects in COX3 are a cause of Leber hereditary optic neuropathy (LHON) and cytochrome c oxidase deficiency (COX deficiency) . Defects in MT-CO3 are also found in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) syndrome and recurrent myoglobinuria.
Partner Proteins
RAC1; LIG4; Htt; SNCA
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
29kDa
Shipping Conditions
Wet Ice
Protein Length
260
NCBI Gene Symbol
COX3
NCBI GB Accession Number
COX3
Host or Source
Rabbit
Nucleotide Accession Number
P00414
Peptide Sequence
FESPFTISDGIYGSTFFVATGFHGLHVIIGSTFLTICFIRQLMFHFTSKH
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