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COX3 Antibody - C-terminal region : Biotin (ARP50251_P050-Biotin)

Selected Variant

ARP50251_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Cytochrome c oxidase III

Gene Aliases

COIII, MTCO3

Gene ID

4514

Accession Number

NP_536849

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human COX3

Target

COX3 is a multi-pass membrane protein. It belongs to the cytochrome c oxidase subunit 3 family. Defects in COX3 are a cause of Leber hereditary optic neuropathy (LHON) and cytochrome c oxidase deficiency (COX deficiency) . Defects in MT-CO3 are also found in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes (MELAS) syndrome and recurrent myoglobinuria.

Partner Proteins

RAC1; LIG4; Htt; SNCA

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

29kDa

Shipping Conditions

Wet Ice

Protein Length

260

NCBI Gene Symbol

COX3

NCBI GB Accession Number

COX3

Host or Source

Rabbit

Nucleotide Accession Number

P00414

Peptide Sequence

FESPFTISDGIYGSTFFVATGFHGLHVIIGSTFLTICFIRQLMFHFTSKH

Price

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