SLAMF6 Antibody - N-terminal region : Biotin (ARP50224_P050-Biotin)
Product Specifications
Gene Name
SLAM family member 6
Gene Aliases
KALI, NTBA, CD352, KALIb, Ly108, NTB-A, SF2000
Gene ID
114836
Swiss Prot
B2R8X8
Accession Number
NP_443163
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human SLAMF6
Target
SLAMF6 is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. SLAMF6 is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs) . It may function as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs) . It may function as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Partner Proteins
SLAMF6; SH2D1A; ZAP70; PTPN6; PTPN11
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
34kDa
References & Citations
Claus, M., (er) Front. Biosci. 13, 956-965 (2008)
Shipping Conditions
Wet Ice
Protein Length
331
NCBI Gene Symbol
SLAMF6
NCBI GB Accession Number
SLAMF6
Host or Source
Rabbit
Protein Name
SLAM family member 6
Nucleotide Accession Number
NM_052931
Peptide Sequence
NFITWLFNETSLAFIVPHETKSPEIHVTNPKQGKRLNFTQSYSLQLSNLK
Frequently Asked Questions
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