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SURF4 Antibody - N-terminal region : FITC (ARP50161_P050-FITC)

Selected Variant

ARP50161_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Surfeit 4

Gene Aliases

ERV29

Gene ID

6836

Swiss Prot

O15260

Accession Number

NP_149351

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SURF4

Target

SURF4 is a conserved integral membrane protein containing multiple putative transmembrane regions. In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs) . The specific function of this protein has not been determined but its yeast homolog is directly required for packaging glycosylated pro-alpha-factor into COPII vesicles. This gene is located in the surfeit gene cluster, which is comprised of very tightly linked housekeeping genes that do not share sequence similarity. The encoded protein is a conserved integral membrane protein containing multiple putative transmembrane regions. In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs) . The specific function of this protein has not been determined but its yeast homolog is directly required for packaging glycosylated pro-alpha-factor into COPII vesicles. This gene uses multiple polyadenylation sites, resulting in transcript length variation. The existence of alternatively spliced transcript variants has been suggested, but their validity has not been determined.

Partner Proteins

UBC; LGR4; MMS19; env; UBL4A; VKORC1; SRSF5; SRSF1; SAFB; S100A9; PSAP; P4HB; NPM1; NHP2L1; NFIA; SEPT2; HSPA5; SEPT7; NDUFB11; HP1BP3; PHGDH; SF3B1; NCSTN; SAP18; SRSF7; TMEM173; UNC93B1; C20orf24; SERINC3; DEGS1

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

30kDa

References & Citations

Mehrle, A., Nucleic Acids Res. 34 (DATABASE ISSUE), D415-D418 (2006)

Shipping Conditions

Wet Ice

Protein Length

269

NCBI Gene Symbol

SURF4

NCBI GB Accession Number

SURF4

Host or Source

Rabbit

Protein Name

Surfeit locus protein 4

Nucleotide Accession Number

NM_033161

Peptide Sequence

GQNDLMGTAEDFADQFLRVTKQYLPHVARLCLISTFLEDGIRMWFQWSEQ

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