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ORAI1 Antibody - middle region : HRP (ARP50118_P050-HRP)

Selected Variant

ARP50118_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

ORAI calcium release-activated calcium modulator 1

Gene Aliases

IMD9, TAM2, ORAT1, CRACM1, TMEM142A

Gene ID

84876

Swiss Prot

Q96D31

Accession Number

NP_116179

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Horse, Pig, Rabbit, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human ORAI1

Target

ORAI1 belongs to the Orai family. ORAI1 (CRACM1) is a plasma membrane protein essential for store-operated calcium entry. Defects in ORAI1 are a cause of severe combined immunodeficiency with CRAC channel dysfunction (CRAC-SCID) .CRACM1 is a plasma membrane protein essential for store-operated calcium entry (Vig et al., 2006 [PubMed 16645049]) .[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-331 BC075831.1 1-331 332-844 BC013386.1 220-732 845-990 BC075831.1 845-990 991-1490 BG574128.1 52-551 1491-1496 AK027372.1 1235-1240

Partner Proteins

UBQLN1; UBC; TRPC3; TRPC6

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Horse: 93%; Human: 100%; Pig: 100%; Rabbit: 100%; Rat: 86%; Yeast: 77%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

33kDa

References & Citations

Peel, S.E., (2008) Am. J. Respir. Cell Mol. Biol. 38 (6), 744-749

Shipping Conditions

Wet Ice

Protein Length

301

NCBI Gene Symbol

ORAI1

NCBI GB Accession Number

ORAI1

Host or Source

Rabbit

Protein Name

Calcium release-activated calcium channel protein 1

Nucleotide Accession Number

NM_032790

Peptide Sequence

IGTLLFLAEVVLLCWVKFLPLKKQPGQPRPTSKPPASGAAANVSTSGITP

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