COL25A1 Antibody - middle region : FITC (ARP50077_P050-FITC)
Product Specifications
Gene Name
Collagen, type XXV, alpha 1
Gene Aliases
AMY, CLAC, CLACP, CFEOM5, CLAC-P
Gene ID
84570
Swiss Prot
Q9BXS0
Accession Number
NP_115907
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human COL25A1
Target
COL25A1 is a brain-specific membrane-bound collagen. Proteolytic processing releases CLAC, a soluble form of COL25A1 containing the extracellular collagen domains that associates with senile plaques in Alzheimer disease (AD) brains. COL25A1 is a brain-specific membrane-bound collagen. Proteolytic processing releases CLAC, a soluble form of COL25A1 containing the extracellular collagen domains that associates with senile plaques in Alzheimer disease (AD; MIM 104300) brains (Osada et al., 2005 [PubMed 15615705]) .[supplied by OMIM].
Partner Proteins
COL25A1; APP; SNCA; IAPP
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 85%; Dog: 100%; Guinea Pig: 80%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 85%; Rabbit: 86%; Rat: 93%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
64kDa
References & Citations
Forsell, C., (er) Neurobiol. Aging (2008) In press
Shipping Conditions
Wet Ice
Protein Length
642
NCBI Gene Symbol
COL25A1
NCBI GB Accession Number
COL25A1
Host or Source
Rabbit
Protein Name
Collagen alpha-1 (XXV) chain
Nucleotide Accession Number
NM_032518
Peptide Sequence
GERGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQ
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