CYP2R1 Antibody - middle region : Biotin (ARP49823_P050-Biotin)
Selected Variant
ARP49823_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Cytochrome P450, family 2, subfamily R, polypeptide 1
Gene Aliases
MGC4663
Gene ID
120227
Swiss Prot
Q6VVX0
Accession Number
NP_078790
Host
Rabbit
Reactivity
Human, Mouse, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human CYP2R1
Target
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor. A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency.
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Zebrafish: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
57kDa
Shipping Conditions
Wet Ice
Protein Length
501
NCBI Gene Symbol
CYP2R1
NCBI GB Accession Number
CYP2R1
Host or Source
Rabbit
Protein Name
Vitamin D 25-hydroxylase
Nucleotide Accession Number
NM_024514
Peptide Sequence
FKQLITNAVSNITNLIIFGERFTYEDTDFQHMIELFSENVELAASASVFL
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