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CYP4F12 Antibody - middle region : HRP (ARP49788_P050-HRP)

Selected Variant

ARP49788_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Cytochrome P450, family 4, subfamily F, polypeptide 12

Gene Aliases

CYPIVF12, F22329_1

Gene ID

66002

Swiss Prot

Q9HCS2

Accession Number

NP_076433

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human CYP4F12

Target

CYP4F12 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. Tt likely localizes to the endoplasmic reticulum. When expressed in yeast the enzyme is capable of oxdizing arachidonic acid; however, its physiological function has not been determined. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein likely localizes to the endoplasmic reticulum. When expressed in yeast the enzyme is capable of oxdizing arachidonic acid; however, its physiological function has not been determined. This gene is part of a cluster of cytochrome P450 genes on chromosome 19.

Partner Proteins

SOD2; HSPA6; UBC

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 79%; Human: 100%; Mouse: 85%; Pig: 79%; Rabbit: 79%; Rat: 79%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

60kDa

References & Citations

Dhar, M., (2008) J. Lipid Res. 49 (3), 612-624

Shipping Conditions

Wet Ice

Protein Length

524

NCBI Gene Symbol

CYP4F12

NCBI GB Accession Number

CYP4F12

Host or Source

Rabbit

Protein Name

Cytochrome P450 4F12

Nucleotide Accession Number

NM_023944

Peptide Sequence

DGRRFHRACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFIDV

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