CYP4F12 Antibody - middle region : Biotin (ARP49788_P050-Biotin)
Product Specifications
Gene Name
Cytochrome P450, family 4, subfamily F, polypeptide 12
Gene Aliases
CYPIVF12, F22329_1
Gene ID
66002
Swiss Prot
Q9HCS2
Accession Number
NP_076433
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human CYP4F12
Target
CYP4F12 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. Tt likely localizes to the endoplasmic reticulum. When expressed in yeast the enzyme is capable of oxdizing arachidonic acid; however, its physiological function has not been determined. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein likely localizes to the endoplasmic reticulum. When expressed in yeast the enzyme is capable of oxdizing arachidonic acid; however, its physiological function has not been determined. This gene is part of a cluster of cytochrome P450 genes on chromosome 19.
Partner Proteins
SOD2; HSPA6; UBC
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 79%; Human: 100%; Mouse: 85%; Pig: 79%; Rabbit: 79%; Rat: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
60kDa
References & Citations
Dhar, M., (2008) J. Lipid Res. 49 (3), 612-624
Shipping Conditions
Wet Ice
Protein Length
524
NCBI Gene Symbol
CYP4F12
NCBI GB Accession Number
CYP4F12
Host or Source
Rabbit
Protein Name
Cytochrome P450 4F12
Nucleotide Accession Number
NM_023944
Peptide Sequence
DGRRFHRACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFIDV
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