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PORCN Antibody - N-terminal region : Biotin (ARP49762_P050-Biotin)

Selected Variant

ARP49762_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Porcupine homolog (Drosophila)

Gene Aliases

PPN, DHOF, FODH, MG61, PORC

Gene ID

64840

Swiss Prot

Q9H237-4

Accession Number

NP_073736

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human PORCN

Target

PORCN belongs to the evolutionarily conserved porcupine (Porc) gene family. Genes of the Porc family encode endoplasmic reticulum proteins with multiple transmembrane domains. Porcupine proteins are involved in the processing of Wnt (wingless and int homologue) proteins. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.This gene belongs to the evolutionarily conserved porcupine (Porc) gene family. Genes of the Porc family encode endoplasmic reticulum proteins with multiple transmembrane domains. Porcupine proteins are involved in the processing of Wnt (wingless and int homologue) proteins. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.

Partner Proteins

WNT5B; WNT3A; WNT6; WNT4; WNT7B; WNT1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

IHC, WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

51kDa

References & Citations

Chen, Z., (2008) Oncogene 27 (24), 3483-3488

Shipping Conditions

Wet Ice

Protein Length

450

NCBI Gene Symbol

PORCN

NCBI GB Accession Number

PORCN

Host or Source

Rabbit

Protein Name

Protein-cysteine N-palmitoyltransferase porcupine

Nucleotide Accession Number

NM_022825

Peptide Sequence

ACRLLWRLGLPSYLKHASTVAGGFFSLYHFFQLHMVWVVLLSLLCYLVLF

Price

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