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NDST4 Antibody - N-terminal region : HRP (ARP49737_P050-HRP)

Selected Variant

ARP49737_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4

Gene Aliases

N-HSST, NDST-4, NHSST4, N-HSST 4

Gene ID

64579

Swiss Prot

Q9H3R1

Accession Number

NP_072091

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human NDST4

Target

NDST4 is an essential bifunctional enzyme that catalyzes both the N-deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. It modifies the GlcNAc-GlcA dissacharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. NDST4 has low deacetylase activity but high sulfotransferase activity.

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

NDST4 is supported by BioGPS gene expression data to be expressed in HepG2

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 90%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

101kDa

References & Citations

Aikawa, J., (2001) J. Biol. Chem. 276 (8), 5876-5882

Shipping Conditions

Wet Ice

Protein Length

872

NCBI Gene Symbol

NDST4

NCBI GB Accession Number

NDST4

Host or Source

Rabbit

Protein Name

Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4

Nucleotide Accession Number

NM_022569

Peptide Sequence

EDWTIFQYNHSTYQPVLLTELQTEKSLSSLSSKTLFATVIQDLGLHDGIQ

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