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SRPRB Antibody - C-terminal region : Biotin (ARP49644_T100-Biotin)

Product Specifications

Gene Name

Signal recognition particle receptor, B subunit

Gene Aliases

APMCF1, SR-beta

Gene ID

58477

Swiss Prot

Q9Y5M8

Accession Number

NP_067026

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human SRPRB

Target

SRPRB has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR) . This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors alpha subunit, a peripheral membrane GTPase, to the ER membrane. SR is required for the cotranslational targeting of both secretory and membrane proteins to the ER membrane.The protein encoded by this gene has similarity to mouse protein which is a subunit of the signal recognition particle receptor (SR) . This subunit is a transmembrane GTPase belonging to the GTPase superfamily. It anchors alpha subunit, a peripheral membrane GTPase, to the ER membrane. SR is required for the cotranslational targeting of both secretory and membrane proteins to the ER membrane.

Partner Proteins

ERLIN2; UBC; STAU1; MDM2; FBXO6; PPP6R1; ADRB2; LMNA; UBL4A; CA9; UBE2L3; TAGLN; SPR; SNRPC; S100A10; RRBP1; RPL38; RFX5; RBMS1; PIN4; PFN1; ACAA1; TMED4; TMEM65; RPS10P5; MRRF; SARNP; NABP2; MRPL14; TMBIM1; SUGP1; SBDS; MRPS28; TARDBP; TOMM40; UBE4B; SF3

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

30kDa

References & Citations

Ewing, R.M., Mol. Syst. Biol. 3, 89 (2007)

Shipping Conditions

Wet Ice

Protein Length

271

NCBI Gene Symbol

SRPRB

NCBI GB Accession Number

SRPRB

Host or Source

Rabbit

Protein Name

Signal recognition particle receptor subunit beta

Nucleotide Accession Number

NM_021203

Peptide Sequence

APAQLGKKGKEFEFSQLPLKVEFLECSAKGGRGDVGSADIQDLEKWLAKI

Subunit

Beta

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