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UGT2B4 Antibody - N-terminal region : HRP (ARP49624_P050-HRP)

Selected Variant

ARP49624_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

UDP glucuronosyltransferase 2 family, polypeptide B4

Gene Aliases

HLUG25, UDPGTH1, UGT2B11, UDPGT2B4, UDPGTh-1

Gene ID

7363

Swiss Prot

P06133

Accession Number

NP_066962

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human UGT2B4

Target

UGT2B4 belongs to the UDP-glycosyltransferase family. UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol) . It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.

Partner Proteins

STAT5A

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

60kDa

References & Citations

Berkhout, M., (2008) Br J Surg 95 (4), 499-505

Shipping Conditions

Wet Ice

Protein Length

528

NCBI Gene Symbol

UGT2B4

NCBI GB Accession Number

UGT2B4

Host or Source

Rabbit

Protein Name

UDP-glucuronosyltransferase 2B4

Nucleotide Accession Number

NM_021139

Peptide Sequence

NIKTILDELVQRGHEVTVLASSASISFDPNSPSTLKFEVYPVSLTKTEFE

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