SPINT2 Antibody - middle region : Biotin (ARP49615_P050-Biotin)
Product Specifications
Gene Name
Serine peptidase inhibitor, Kunitz type, 2
Gene Aliases
PB, Kop, HAI2, DIAR3, HAI-2
Gene ID
10653
Swiss Prot
O43291
Accession Number
NP_066925
Host
Rabbit
Reactivity
Human, Yeast
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human SPINT2
Target
HAI-2 (SPINT2) is a candidate tumour suppressor gene that is frequently hypermethylated and underexpressed in human HCCs, and the KD-1 domain of HAI-2 is the key region responsible for its anti-invasive function. It is also implicated in human cervical cancer.
Partner Proteins
TUBG1; APP; UBC; SUMO4; HGFAC; ITIH3; CTSB; ITIH2
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Human: 100%; Yeast: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
28kDa
References & Citations
Generali, D., Clin. Cancer Res. 13 (2 PT 1), 550-558 (2007)
Shipping Conditions
Wet Ice
Protein Length
252
NCBI Gene Symbol
SPINT2
NCBI GB Accession Number
SPINT2
Host or Source
Rabbit
Protein Name
Kunitz-type protease inhibitor 2
Nucleotide Accession Number
NM_021102
Peptide Sequence
MLRCFRQQENPPLPLGSKVVVLAGLFVMVLILFLGASMVYLIRVARRNQE
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