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NLGN4X Antibody - middle region : Biotin (ARP49557_P050-Biotin)

Product Specifications

Gene Name

Neuroligin 4, X-linked

Gene Aliases

HLNX, HNL4X, NLGN4, ASPGX2, AUTSX2

Gene ID

57502

Swiss Prot

Q8NFZ3

Accession Number

NP_065793

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human NLGN4X

Target

NLGN4X is a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. It interacts with discs, large (Drosophila) homolog 4 (DLG4) . NLGN4X might play a role in the autism and Asperger syndrome.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests. This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs, large (Drosophila) homolog 4 (DLG4) . Mutations in this gene have been associated with autism and Asperger syndrome. Two transcript variants encoding the same protein have been identified for this gene.

Partner Proteins

DLGAP2; DLG4

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

92kDa

References & Citations

Wermter, A.K., Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B (4), 535-537

Shipping Conditions

Wet Ice

Protein Length

816

NCBI Gene Symbol

NLGN4X

NCBI GB Accession Number

NLGN4X

Host or Source

Rabbit

Protein Name

Neuroligin-4, Y-linked

Nucleotide Accession Number

NM_020742

Peptide Sequence

ELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFE

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