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HLA-DQA2 Antibody - middle region : HRP (ARP49465_P050-HRP)

Selected Variant

ARP49465_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Major histocompatibility complex, class II, DQ alpha 2

Gene Aliases

HLA-DCA, HLA-DXA, HLADQA2, DC-alpha, DX-ALPHA

Gene ID

3118

Swiss Prot

P01906

Accession Number

NP_064440

Host

Rabbit

Reactivity

Human, Mouse, Cow, Goat, Horse, Pig, Rabbit, Sheep

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human HLA-DQA2

Target

This gene belongs to the HLA class II alpha chain family. The encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B lymphocytes, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells.

Partner Proteins

UBC; HLA-DQB1; CD4; INS

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Goat: 86%; Horse: 86%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 86%; Sheep: 86%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

28kDa

Shipping Conditions

Wet Ice

Protein Length

255

NCBI Gene Symbol

HLA-DQA2

NCBI GB Accession Number

HLA-DQA2

Host or Source

Rabbit

Protein Name

HLA class II histocompatibility antigen, DQ alpha 2 chain

Nucleotide Accession Number

NM_020056

Peptide Sequence

LPMFSKFISFDPQSALRNMAVGKHTLEFMMRQSNSTAATNEVPEVTVFSK

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