TRPV5 Antibody - N-terminal region : Biotin (ARP49457_P050-Biotin)
Selected Variant
ARP49457_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Transient receptor potential cation channel, subfamily V, member 5
Gene Aliases
CAT2, ECAC1, OTRPC3
Gene ID
56302
Swiss Prot
Q9NQA5
Accession Number
NP_062815
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human TRPV5
Target
TRPV5 constitutively active calcium selective cation channel thought to be involved in Ca (2+) reabsorption in kidney and intestine. The channel is activated by low internal calcium level and the current exhibits an inward rectification. A Ca (2+) - dependent feedback regulation includes fast channel inactivation and slow current decay. Heteromeric assembly with TRPV6 seems to modify channel properties. TRPV5-TRPV6 heteromultimeric concatemers exhibit voltage-dependent gating.
Partner Proteins
EWSR1; CALB1; S100A10; ANXA2
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity purified
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
80kDa
Shipping Conditions
Wet Ice
Protein Length
729
NCBI Gene Symbol
TRPV5
NCBI GB Accession Number
TRPV5
Host or Source
Rabbit
Protein Name
Transient receptor potential cation channel subfamily V member 5
Peptide Sequence
GFLPKAEGPGSQLQKLLPSFLVREQDWDQHLDKLHMLQQKRILESPLLRA
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