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LRRC8A Antibody - middle region : FITC (ARP49453_P050-FITC)

Selected Variant

ARP49453_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Leucine rich repeat containing 8 family, member A

Gene Aliases

AGM5, LRRC8, SWELL1, HsLRRC8A

Gene ID

56262

Swiss Prot

Q8IWT6

Accession Number

NP_062540

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human LRRC8A

Target

LRRC8A is a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. LRRC8A is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation.

Partner Proteins

SDHA; ELAVL1; UBC

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 79%; Rat: 93%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

94kDa

Shipping Conditions

Wet Ice

Protein Length

810

NCBI Gene Symbol

LRRC8A

NCBI GB Accession Number

LRRC8A

Host or Source

Rabbit

Protein Name

Leucine-rich repeat-containing protein 8A

Nucleotide Accession Number

NM_019594

Peptide Sequence

NLTQIELRGNRLECLPVELGECPLLKRSGLVVEEDLFNTLPPEVKERLWR

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