ALG1 Antibody - N-terminal region : Biotin (ARP49445_P050-Biotin)

Product Specifications

Gene Name

Asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog (S. cerevisiae)

Gene Aliases

HMT1, MT-1, CDG1K, HMAT1, HMT-1, Mat-1, hMat-1

Gene ID

56052

Swiss Prot

Q9BT22

Accession Number

NP_061982

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Rabbit, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human ALG1

Target

ALG1 catalyzes the first mannosylation step in the biosynthesis of lipid-linked oligosaccharides. Defects in ALG1 are the cause of congenital disorder of glycosylation type 1K (CDG1K) .The biosynthesis of lipid-linked oligosaccharides is highly conserved among eukaryotes and is catalyzed by 14 glycosyltransferases in an ordered stepwise manner. Mannosyltransferase I (MT I) catalyzes the first mannosylation step in this process.[supplied by OMIM]. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-421 BM767933.1 1-421 422-1179 AY359073.1 416-1173 1180-1444 CA455103.1 259-523 1445-1939 CD366777.1 17-511 c 1940-2122 BC031095.1 1931-2113 2123-2149 BQ002699.1 1-27 c

Partner Proteins

UBC; FBXO6; BAG3; MMS19

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 79%; Human: 100%; Mouse: 85%; Rabbit: 79%; Rat: 79%; Yeast: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.