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PAK2 Antibody - N-terminal region : Biotin (ARP49217_P050-Biotin)

Selected Variant

ARP49217_P050-Biotin

Size: 100 µL

Product Specifications

Gene Aliases

PAK65, PAKgamma

Gene ID

5062

Swiss Prot

Q13177

Accession Number

NP_002568

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human PAK2

Target

The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.

Partner Proteins

RHOJ; SORBS3; CDC42; UBC; NPEPPS; YWHAZ; YWHAH; YWHAG; YWHAE; YWHAB; TGM2; PFAS; PAFAH1B1; LDHB; ZFYVE19; UBFD1; UBE2R2; SCLY; ISOC1; ERP44; SFN; G6PD; EEF2; CKB; CAPNS1; PAK1; PAK2; HSPA5; RIOK3; MYC; APP; SH3RF3; ARHGEF7; SRC; LCK; HCK; RAC1; HIST1H4F

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

57kDa

Shipping Conditions

Wet Ice

Protein Length

524

NCBI Gene Symbol

PAK2

NCBI GB Accession Number

PAK2

Host or Source

Rabbit

Peptide Sequence

DNGELEDKPPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEEKKPRHK

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