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GGTL3 Antibody - C-terminal region : HRP (ARP49139_P050-HRP)

Selected Variant

ARP49139_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Gamma-glutamyltransferase 7

Gene Aliases

GGT4, GGTL3, GGTL5, D20S101

Gene ID

2686

Swiss Prot

B5MD39

Accession Number

NP_821158

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human GGTL3

Target

GGTL3 is an enzymes involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. GGTL3 consists of a heavy and a light chain, and it can interact with CT120, a plasma membrane-associated protein that is possibly involved in lung carcinogenesis.This gene is a member of a gene family that encodes enzymes involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene consists of a heavy and a light chain, and it can interact with CT120, a plasma membrane-associated protein that is possibly involved in lung carcinogenesis. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

Partner Proteins

TMEM242; LHFPL5; MALL; GPR25; FAM96B; DCP2; GGT7; FAM57A

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

70kDa

References & Citations

Heisterkamp, N., (2008) Hum. Genet. 123 (4), 321-332

Shipping Conditions

Wet Ice

Protein Length

662

NCBI Gene Symbol

GGT7

NCBI GB Accession Number

GGT7

Host or Source

Rabbit

Protein Name

Putative gamma-glutamyltransferase light chain 3

Nucleotide Accession Number

NM_178026

Peptide Sequence

ILLNSQMLDFSWPNRTANHSAPSLENSVQPGKRPLSFLLPTVVRPAEGLC

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