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CHSY-2 Antibody - N-terminal region : FITC (ARP49126_P050-FITC)

Selected Variant

ARP49126_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Chondroitin sulfate synthase 3

Gene Aliases

CSS3, CHSY2

Gene ID

337876

Swiss Prot

Q70JA7

Accession Number

NP_787052

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human CHSY-2

Target

CHSY-2 has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. CHSY-2 transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Specific activity of CHSY-2 is much reduced compared to CHSY1.CSS3 is a glycosyltransferase that has both glucuronyltransferase and N-acetylgalactosaminyltransferase activities (Yada et al., 2003 [PubMed 12907687]) .[supplied by OMIM].

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 86%; Human: 100%; Mouse: 79%; Rabbit: 100%; Rat: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

100kDa

References & Citations

Izumikawa, T., (2007) Biochem. J. 403 (3), 545-552

Shipping Conditions

Wet Ice

Protein Length

882

NCBI Gene Symbol

CHSY3

NCBI GB Accession Number

CHSY3

Host or Source

Rabbit

Protein Name

Chondroitin sulfate synthase 3

Nucleotide Accession Number

NM_175856

Peptide Sequence

PPLQQRRRGREPEGATGLPGAPAAEGEPEEEDGGAAGQRRDGRPGSSHNG

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